Definitions
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Etymologies
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Examples
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Cyclin is the main switch that turns the "CDK engine" on and off.
The Nobel Prize in Physiology or Medicine 2001 - Presentation Speech 2001
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Pitx2 associates with a ribonucleoprotein complex that includes the mRNA stabilizing factor HuR and sustains Ccnd1 (also known as Cyclin D1) expression, thereby prolonging its mRNA half-life.
Naturejobs - All Jobs R Gherzi 2010
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They found that Fbx4, a naturally occurring protein, plays a key role in stopping production of another protein called Cyclin D1, which is believed to contribute to the early stages of cancer development.
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Cyclin' Missy, he does indeed have a skirt guard, probably because he is posing with a ladies bike.
To Whom It May Concern: Letting Things Take Care of Themselves BikeSnobNYC 2010
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Cyclin' Missy, the things you will do to score some Loratabs.
Metamorphosis: The More Things Change, The More They Shouldn't BikeSnobNYC 2009
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We demonstrate that the mitotic cyclin-dependent kinase cdc2/CDK1 is the kinase responsible for phosphorylating these sites, and its mitotic partner Cyclin B efficiently coimmunoprecipitates with raptor in mitotic cells.
PLoS ONE Alerts: New Articles Dana M. Gwinn et al. 2010
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CENTG1, is amplified in 19% of the GBM cases, and is is frequently co-amplified with Cyclin-dependent kinase 4 (CDK4) in a variety of human cancers, including sarcoma, glioblastoma, and neuroblastoma
PLoS ONE Alerts: New Articles Ethan Cerami et al. 2010
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Erlotinib did best against EGFR mutations, vandetanib for high VEGFR-2 expression and the erlotinib-bexarotene fared best with Cyclin D1 defects or amplified numbers of the EGFR gene.
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We demonstrate that the mitotic cyclin-dependent kinase cdc2/CDK1 is the kinase responsible for phosphorylating these sites, and its mitotic partner Cyclin B efficiently coimmunoprecipitates with raptor in mitotic cells.
PLoS ONE Alerts: New Articles Dana M. Gwinn et al. 2010
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Costello JF, Plass C, Arap W, Chapman VM, Held WA, et al. (1997) Cyclin-dependent kinase 6 (cdk6) amplification in human gliomas identified using two-dimensional separation of genomic dna.
PLoS ONE Alerts: New Articles Ethan Cerami et al. 2010
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