Definitions
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Etymologies
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Examples
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Wehenkel M, Hong JT, Kim KB (2008) Proteasome modulators: essential chemical genetic tools for understanding human diseases.
PLoS ONE Alerts: New Articles Michele Mishto et al. 2010
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More information: Enhancement of Proteasome Activity by a Small-Molecule Inhibitor of Usp14, Nature, Volume 467, issue 7312, pp 179-184
PhysOrg.com - latest science and technology news stories 2010
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Proteasome degradation is the key step in the production of MHC class I-restricted epitopes and therefore its activity could be an important element in the activation and regulation of autoreactive CD8+ T cells in Multiple Sclerosis.
PLoS ONE Alerts: New Articles Michele Mishto et al. 2010
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Table 9 Proteasome inhibitors in anticancer development
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Proteasome inhibitors (PIs) have clinical activity in hematological tumors, and inhibitors of autophagy are also being evaluated as potential antitumor therapies.
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Proteasome degradation is the key step in the production of MHC class I-restricted epitopes and therefore its activity could be an important element in the activation and regulation of autoreactive CD8+ T cells in Multiple Sclerosis.
PLoS ONE Alerts: New Articles Michele Mishto et al. 2010
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Dimayuga E, Keller JN (2006) Proteasome regulation of oxidative stress in aging and age-related diseases of the CNS.
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"Proteasome inhibitors are currently being used to treat some types of cancer, including multiple myelomas, although many aspects of this cellular process remain poorly understood," said the paper's senior author, Linda Hendershot, PhD, Genetics and Tumor Cell Biology.
unknown title 2009
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"Proteasome inhibitors are currently being used to treat some types of cancer, including multiple myelomas, although many aspects of this cellular process remain poorly understood," said the paper's senior author, Linda Hendershot, PhD, Genetics and Tumor Cell Biology.
unknown title 2009
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"Proteasome inhibitors are currently being used to treat some types of cancer, including multiple myelomas, although many aspects of this cellular process remain poorly understood," said the paper's senior author, Linda Hendershot, PhD, Genetics and Tumor Cell Biology.
unknown title 2009
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