Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun A polyomavirus found in humans and other mammals that causes tumors in certain species, such as hamsters and rats, and various diseases in immunocompromised monkeys. It has been widely researched as a model of viral replication and gene expression and a possible cause of certain cancers in humans.
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
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Examples
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The polio vaccine used in the late 1950s and early 1960s was contaminated with a monkey virus called simian virus 40 (SV40) present in monkey kidney cells used to grow the vaccine.
SV40 2010
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SV40 has not been present in any vaccine since 1963.
SV40 2010
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SV40 was present in cancers of people who either had or had not received the polio vaccine that was contaminated with SV40.
SV40 2010
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Using current techniques, it is difficult to distinguish SV40 virus from other common and related viruses.
SV40 2010
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People with cancers who were born after SV40 was no longer a contaminant of the polio vaccine were found to have evidence for SV40 in their cancerous cells.
SV40 2010
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Taken together, these findings do not support the hypothesis that SV40 virus contained in polio vaccines administered before 1963 cause cancers.
SV40 2010
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In addition, available evidence suggests that SV40 virus is likely be transmitted to people by a mechanism other than vaccines.
SV40 2010
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Recently, investigators found SV40 DNA in biopsy specimens obtained from patients with cancers such as mesothelioma (lung), osteosarcoma (bone) and non-Hodgkins lymphoma (lymph nodes).
SV40 2010
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* Other cancer-causing viruses, such as SV40 and human papillomavirus HPV, would eventually be discovered in 1960 and 1983, respectively.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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* Other cancer-causing viruses, such as SV40 and human papillomavirus HPV, would eventually be discovered in 1960 and 1983, respectively.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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