amino-terminal love

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • adjective biochemistry Describing the amino acid, at one end of a polypeptide or protein, that has a free amino group

Etymologies

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Examples

  • (…) Working with a CRD called NW1 from a different protein (NOWA) of Hydra, they show that their CRD can be converted by single amino acid changes from a structure that resembles the amino-terminal CRD of minicollagen-1 to a structure that resembles the alternative conformation seen in the carboxyterminal CRD of minicollagen-1. carrie

    Axe (2004) and the evolution of enzyme function - The Panda's Thumb 2007

  • In Anfinsen's early work, he and Steinberg studied the non-uniform labelling in newly synthesized proteins - a technique which later permitted Dintzis, Canfield and others to determine that proteins are synthesized sequentially from the amino-terminal and in vivo, and to calculate the rate at which amino acids are polymerized.

    Christian Anfinsen - Biography 1973

  • "This is the first time anybody has identified a unique domain within the amino-terminal region of the CagA protein, and it will help us to better understand how this oncogenic protein functions," Chen said.

    PhysOrg.com - latest science and technology news stories 2010

  • Each variable exon encodes a signal peptide and the amino-terminal aglycone-recognition domain.

    PLoS ONE Alerts: New Articles Haiyan Huang et al. 2010

  • Secretory and membrane proteins usually contain an amino-terminal signal peptide, which is recognized by the signal recognition particle (SRP) when nascent polypeptide chains emerge from the ribosome.

    Naturejobs - All Jobs Claudia Y. Janda 2010

  • "This is the first time anybody has identified a unique domain within the amino-terminal region of the CagA protein, and it will help us to better understand how this oncogenic protein functions," Chen said.

    innovations-report 2010

  • This enzyme contains an amino-terminal signal sequence (Pre) that directs it to the secretory pathway via the endoplasmic reticulum (ER) and a propeptide (Pro) that maintains it as inactive zymogen

    PLoS ONE Alerts: New Articles Virginie Renaud et al. 2010

  • Castaño EM, Frangione B, Inestrosa NC (1995) The α-helical to β-strand transition in the amino-terminal fragment of the amyloid β-peptide modulates amyloid formation.

    PLoS ONE Alerts: New Articles Carlene S. Starck et al. 2010

  • Identification of new regulators of mitochondrial fusion using a novel quantitative bi-molecular complementation assay. (a) Mitochondria from two cell lines expressing either the amino-terminal part of luciferase or its carboxy-terminal part are isolated.

    BioMed Central - Latest articles Alexis Jourdain 2010

  • (ROKβ) and ROCK-2 (ROKα) which contain highly conserved amino-terminal and substantially different carboxy-terminal domains

    PLoS ONE Alerts: New Articles Tzu-Ching Chang et al. 2010

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