autophagosomes love

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Plural form of autophagosome.

Etymologies

Sorry, no etymologies found.

Examples

  • These "garbage bags" (more formally known as autophagosomes) then travel to enzyme-filled sacs known as lysosomes that fuse with the bags and digest their cargo.

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  • Autophagy is a catabolic process whereby unwanted and/or damaged cellular components are engulfed by membranous structures, termed autophagosomes, to be degraded and recycled.

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  • They found that just 30 minutes of activity on a treadmill-like device increased the number of autophagosomes -- a collection of molecules that form around cellular parts that are available for recycling -- in mouse muscle tissue.

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  • The process of autophagy involves the formation of autophagosomes, double-membrane structures that encapsulate cytosol.

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  • Dr. Cuervo and her team found that the defective huntingtin proteins stick to the inner layer of autophagosomes, preventing them from gathering garbage.

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  • The present results suggest that the association of EGFP-tagged Irgm1 with autophagosomes may result from transfer of the protein from lysosomes or other compartments of the endocytic system, but not from the Golgi apparatus, where the fusion protein fails to localize.

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  • Autophagy involves the sequestration of cytoplasmic contents into autophagosomes for traffic to lysosomes for degradation.

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  • It has been reported that Irgm1-EGFP (pF25) co-localised with MDC and LC3 positive compartments, suggesting that Irgm1 associates with autophagosomes and therefore has a pro-autophagy function in macrophages

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  • Although autophagy is antiapoptotic, increased numbers of autophagosomes have been associated with forms of non-apoptotic cell death.

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  • Sarah Pfau, who earned her bachelor's degree from Princeton in 2008, exposed the cells to a fluorescently labeled antibody that recognizes a protein present on autophagosomes, the structures that cells form to perform autophagy.

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