Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun A
coenzyme produced within the body, anoxidized degradation product oftetrahydrobiopterin . Defects in biopterinsynthesis orregeneration can cause a form ofhyperphenylalaninemia , and biopterindeficiency has been associated withdystonia andrabies .
Etymologies
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Examples
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As the enzyme is secreted, the host may supply the biopterin cofactor.
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Wachter, H.; Werner, E.R.: Stimulation of human nitric oxide synthase by tetrahydro - biopterin and selective binding of the cofactor.
Recently Uploaded Slideshows arab2000.forumpro.fr@slideshare.net(arab2000.forum 2009
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T. gondii has been shown to encode a functional pterin-4a-carbinolamine dehydratase involved in recycling biopterin but dihydropterin reductase has not been detected
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The presence or absence of a biopterin synthetic pathway and its recycling are currently under investigation (37,38).
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T. gondii enzymes exhibited an absolute requirement for biopterin for activity using the stable tetrahydrobiopterin analog 6-MPH
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The residues present in the active site that interact with the aromatic amino acid substrate and biopterin cofactor are highlighted with black triangles.
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As relatively few enzymes require biopterin for activity, the discovery of a biopterin-dependent enzyme raises the issue of the possible sources of biopterin for this enzyme.
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As the reproducibility of biopterin-dependent enzyme kinetics are greatly affected by the instability of the biopterin cofactor, 6-MPH
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Indeed, human GTP cyclohydrolase, limiting in biopterin synthesis, has been found to be elevated in.
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The residues that interact with the biopterin cofactor and amino acid substrates in the rat TyrH (tyrosine hydroxylase) sequence
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