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Examples
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Moore and Stein had determined the amino-acid sequence of ribonuclease, but they received the prize for discovering anomalous properties of functional groups in the enzyme's active site, which is a result of the protein fold.
The Nobel Prize in Chemistry: The Development of Modern Chemistry 2010
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In fact, some companies -- including Geron -- are pursuing the idea that inhibiting the enzyme's activity may actually help treat cancer.
Arlene Weintraub: Scientists Can Reverse Aging In Mice, But Can They Do It For Humans? Arlene Weintraub 2010
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In fact, some companies -- including Geron -- are pursuing the idea that inhibiting the enzyme's activity may actually help treat cancer.
Arlene Weintraub: Scientists Can Reverse Aging in Mice, But Can They Do it for Humans? Arlene Weintraub 2010
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In fact, some companies -- including Geron -- are pursuing the idea that inhibiting the enzyme's activity may actually help treat cancer.
Arlene Weintraub: Scientists Can Reverse Aging In Mice, But Can They Do It For Humans? Arlene Weintraub 2010
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What's your prediction if I radically change the size of a conserved residue (from one of the largest to the smallest) in an enzyme's active site, by substituting a residue not found in nature?
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I asked: What's your prediction if I radically change the size of a conserved residue (from one of the largest to the smallest) in an enzyme's active site, by substituting a residue not found in nature?
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Specificity is a function of the enzyme's structure and its catalytic sites.
Biotransformation 2008
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What's your prediction if I radically change the size of a conserved residue (from one of the largest to the smallest) in an enzyme's active site, by substituting a residue not found in nature?
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As shown in Figure 1, when a substrate fits into the enzyme's structure, an enzyme-substrate complex can be formed.
Biotransformation 2008
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Mice regained the ability to form new memories when the enzyme's function was elevated.
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