Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A calcium-dependent actin-binding protein that modulates actin filament length and gelation and thus influences the structure of the cytoskeleton and plays a key role in cellular motility and differentiation.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biology An actin-binding protein that is a key regulator of actin filament assembly and disassembly.

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[gel(ation) + sol- (as in dissolve, from its turning actin from a semi-solid into a fluid) + –in.]

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Examples

  • Arai M, Bandura JL, Kwiatkowski DJ (1998) Advillin (p92): a new member of the gelsolin/villin family of actin regulatory proteins.

    PLoS ONE Alerts: New Articles Ethan Cerami et al. 2010

  • The mechanism of BCL2 regulation of cell adhesion and motility may involve formation of a complex containing BCL2, actin, and gelsolin, which appears to functionally decrease the severing activity of gelsolin.

    Naturejobs - All Jobs Hengning Ke 2010

  • Thus, the formation of BCL2 and gelsolin complexes (which possibly contain other proteins) appears to play a critical role in the regulation of cell adhesion and migration.

    Naturejobs - All Jobs Hengning Ke 2010

  • The mechanism of BCL2 regulation of cell adhesion and motility may involve formation of a complex containing BCL2, actin, and gelsolin, which appears to functionally decrease the severing activity of gelsolin.

    Naturejobs - All Jobs Hengning Ke 2010

  • The mechanism of BCL2 regulation of cell adhesion and motility may involve formation of a complex containing BCL2, actin, and gelsolin, which appears to functionally decrease the severing activity of gelsolin.

    Naturejobs - All Jobs Hengning Ke 2010

  • Thus, the formation of BCL2 and gelsolin complexes (which possibly contain other proteins) appears to play a critical role in the regulation of cell adhesion and migration.

    Naturejobs - All Jobs Hengning Ke 2010

  • Thus, the formation of BCL2 and gelsolin complexes (which possibly contain other proteins) appears to play a critical role in the regulation of cell adhesion and migration.

    Naturejobs - All Jobs Hengning Ke 2010

  • Arai M, Bandura JL, Kwiatkowski DJ (1998) Advillin (p92): a new member of the gelsolin/villin family of actin regulatory proteins.

    PLoS ONE Alerts: New Articles Ethan Cerami et al. 2010

  • Then there’s gelsolin, glyceraldye 3 phosphate dehydrogenase, alpha enolase, argininosuccinate lyase, NADPH dependent reductase.

    Vacuity of ID: Comments on Irreducible Complexity - The Panda's Thumb 2006

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