Definitions
Wiktionary
- n. That which intercalates
- n. biochemistry Any of several classes of small molecule that insert themselves into the structure of DNA
Examples
“AS1413 (amonafide L-malate) is a DNA intercalator that induces apoptotic signalling by blocking Topoisomerase II binding to DNA.”
“* #3665 The novel DNA intercalator amonafide (AS1413) disrupts the cell cycle by mechanisms distinct from topo II inhibitors daunorubicin and etoposide (Senderovich et al.)”
“Hud and his research team discovered that by using a molecule that can bind in between two neighboring base pairs of DNA, known as an intercalator, they can bring short pieces of DNA and RNA together in a manner that helps them create much longer molecules.”
“The problem is known as strand cyclization, but Hud and his team discovered that using a molecule that binds between neighboring base pairs of DNA, known as an intercalator, can bring short pieces of DNA and RNA together in a manner that helps them create much longer molecules.”
Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7
“The problem is known as strand cyclisation, but Hud and his team discovered that using a molecule that binds between neighboring base pairs of DNA, known as an intercalator, can bring short pieces of DNA and RNA together in a manner that helps them create much longer molecules.”
“AS1413 is a novel DNA intercalator that induces apoptotic signalling by blocking topoisomerase II binding to DNA.”
“For an intercalator to fit between base pairs, the bases must separate, distorting the DNA strand by unwinding of the double helix.”
“If you have the intercalator present, you can get polymers.”
“With no intercalator, it doesn't work, it's that simple, "Hud explained.”
“With no intercalator, it doesn't work, it's that simple, "said Hud.”
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