Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun organic chemistry An inhibitor of phosphodiesterase III that potentiates the effect of cyclic adenosine monophosphate.

Etymologies

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Examples

  • Administration of dobutamine or milrinone often requires very close monitoring in the hospital's cardiac or intensive care unit setting due to the life-threatening safety risks associated with these drugs, including ventricular/atrial arrhythmias, hypotension, sudden cardiac death, and other potential adverse long term outcomes.

    The Earth Times Online Newspaper 2010

  • In order to improve the hemodynamic profile of the heart and increase cardiac contractility, a physician may also administer an intravenous inotropic agent such as dobutamine (beta-adrenergic agonist) or milrinone (PDE3-inhibitor).

    The Earth Times Online Newspaper 2010

  • After a bolus (50 µg / kg) and infusion (0.5 µg / kg / m) of milrinone, cardiac and right and left ventricular stroke work indices improved significantly with little change in HR.

    Recently Uploaded Slideshows 2009

  • There has been one published study158 evaluating milrinone in pediatric patients with sepsis.

    Recently Uploaded Slideshows 2009

  • Barton P, Garcia J, Kouatli A, et al. Hemodynamic effects of i.v. milrinone lactate in pediatric patients with septic shock.

    Recently Uploaded Slideshows 2009

  • Sole use of inotropic agents that also have vasodilatory activity (e.g. isoproterenol, milrinone) are likely to reduce blood pressure.

    Recently Uploaded Slideshows 2009

  • Inamrinone (previously named amrinone) and milrinone are inhibitors of PDE-3 and have been studied for use in the treatment of

    Citizendium, the Citizens' Compendium - Recent changes [en] 2008

  • Then the oocytes were arrested at GV by 2.5 µM milrinone for 24 hours before meiosis resumption.

    PLoS ONE Alerts: New Articles Shen Yin et al. 2008

  • The oocytes were collected in M2 medium supplemented with 2.5 µM milrinone

    PLoS ONE Alerts: New Articles Shen Yin et al. 2008

  • "A comparison of oral milrinone, digoxin, and their combination in the treatment of patients with chronic heart failure".

    Citizendium, the Citizens' Compendium - Recent changes [en] 2008

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