Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun organic chemistry An
inhibitor ofphosphodiesterase III thatpotentiates the effect of cyclic adenosine monophosphate.
Etymologies
Sorry, no etymologies found.
Support
Help support Wordnik (and make this page ad-free) by adopting the word milrinone.
Examples
-
Administration of dobutamine or milrinone often requires very close monitoring in the hospital's cardiac or intensive care unit setting due to the life-threatening safety risks associated with these drugs, including ventricular/atrial arrhythmias, hypotension, sudden cardiac death, and other potential adverse long term outcomes.
-
In order to improve the hemodynamic profile of the heart and increase cardiac contractility, a physician may also administer an intravenous inotropic agent such as dobutamine (beta-adrenergic agonist) or milrinone (PDE3-inhibitor).
-
After a bolus (50 µg / kg) and infusion (0.5 µg / kg / m) of milrinone, cardiac and right and left ventricular stroke work indices improved significantly with little change in HR.
-
There has been one published study158 evaluating milrinone in pediatric patients with sepsis.
-
Barton P, Garcia J, Kouatli A, et al. Hemodynamic effects of i.v. milrinone lactate in pediatric patients with septic shock.
-
Sole use of inotropic agents that also have vasodilatory activity (e.g. isoproterenol, milrinone) are likely to reduce blood pressure.
-
Inamrinone (previously named amrinone) and milrinone are inhibitors of PDE-3 and have been studied for use in the treatment of
Citizendium, the Citizens' Compendium - Recent changes [en] 2008
-
Then the oocytes were arrested at GV by 2.5 µM milrinone for 24 hours before meiosis resumption.
PLoS ONE Alerts: New Articles Shen Yin et al. 2008
-
The oocytes were collected in M2 medium supplemented with 2.5 µM milrinone
PLoS ONE Alerts: New Articles Shen Yin et al. 2008
-
"A comparison of oral milrinone, digoxin, and their combination in the treatment of patients with chronic heart failure".
Citizendium, the Citizens' Compendium - Recent changes [en] 2008
Comments
Log in or sign up to get involved in the conversation. It's quick and easy.