Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun Plural form of
minichromosome .
Etymologies
Sorry, no etymologies found.
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Examples
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Together they decided to test if telomere DNA from Tetrahymena could protect minichromosomes in yeast.
The 2009 Nobel Prize in Physiology or Medicine - Illustrated Presentation 2009
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Szostak coupled it to the minichromosomes and put them back into yeast cells.
The 2009 Nobel Prize in Physiology or Medicine - Press Release 2009
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Jack Szostak studied yeast cells and observed that linear artificial minichromosomes were rapidly degraded.
The 2009 Nobel Prize in Physiology or Medicine - Illustrated Presentation 2009
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The results, which were published in 1982, were striking – the telomere DNA sequence protected the minichromosomes from degradation.
The 2009 Nobel Prize in Physiology or Medicine - Press Release 2009
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Over the last few years biotech laboratories and industry have developed two new techniques – artificial minichromosomes and transformed organelles – which, the industry claims, will allow it to overcome the problems it has faced until now with GMOs, especially their low efficiency and genetic contamination.
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One characteristic of natural and artificial minichromosomes that has attracted the attention of biotechnologists is that they seem to be more "independent" from the rest of the genetic material than larger nucleus chromosomes.
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Industry and labs developing and using the technology thus claim that minichromosomes will avoid the side-effects of genetic engineering because there will be no disruption of genetic material.
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There are natural minichromosomes too, and they are encountered widely among different species and kingdoms.
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Once inserted into the cell, artificial minichromosomes also remain physically independent from other chromosomes and genetic material; they are not incorporated into the native DNA and therefore do not cause mutations in the native DNA.
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Artificial minichromosomes can be built and inserted into all kind of species, from yeast and bacteria, to higher plants, insects, mammals and humans.
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