“The idea was that the same defect in monoubiquitination of the histone may affect also protein degradation which involves polyubiquitination, though it was clear that the single modification of the histone molecule by ubiquitin does not lead to its targeting to proteolysis.”
“Indeed, as reported this week in Cell, human Rad6 can functionally replace yeast Rad6, and H2B monoubiquitination in humans functions by the same histone crosstalk mechanism as it does in yeast, demonstrating the conservation in this system from yeast to humans.”
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monoubiquitylation, monoubiquitination, epidemiological, hematopericardium, psychophysiological, encephalomyelitis, palaeopalynology, encephalomyelitic, actuopalynology, paleopalynology, melissopalynology, melitopalynology and 169 more...
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