Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A serine proteinase inhibitor that is expressed in neurons during embryogenesis and in the adult nervous system

Etymologies

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Examples

  • Lawrence DA (2004) Tissue-type plasminogen activator and neuroserpin: a well-balanced act in the nervous system?

    PLoS ONE Alerts: New Articles Hongqi Xin et al. 2010

  • Inhibition of the proteasome with MG132 reveals that both mutant neuroserpin

    Journal of Biological Chemistry current issue Kroeger, H., Miranda, E., MacLeod, I., Perez, J., 2009

  • We have used transient transfection of COS7 cells and mouse embryonic fibroblasts, PC12 cell lines that conditionally express wild type and mutant neuroserpin and fly models of FENIB to assess the cellular handling of wild type and mutant serpins.

    Journal of Biological Chemistry current issue Kroeger, H., Miranda, E., MacLeod, I., Perez, J., 2009

  • At steady state, the fractions of intracellular polymerogenic G392E mutant neuroserpin in the monomeric and polymeric states are comparable.

    Journal of Biological Chemistry current issue Kroeger, H., Miranda, E., MacLeod, I., Perez, J., 2009

  • [69]. tPA expression as well as its inhibitors PAI-1 and neuroserpin are up-regulated in the acute stage of cerebral ischemia and hemorrhage

    PLoS ONE Alerts: New Articles Hongqi Xin et al. 2010

  • With specific inhibitors, i.e., plasminogen activator inhibitor (PAI) -1 (encoded by serpine 1 gene, secreted by neurons and active astrocytes) and neuroserpin (encoded by

    PLoS ONE Alerts: New Articles Hongqi Xin et al. 2010

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