from The American Heritage® Dictionary of the English Language, 4th Edition
- n. Chiefly British Phenobarbital.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. A barbiturate drug used as a sedative.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. a long-acting barbiturate used as a sedative
Sorry, no etymologies found.
Most contain belladonna or something like it (atropine, hyoscyamine) and often phenobarbital (phenobarbitone).
- Do not mix in the same syringe with barbiturates (thiopentone, phenobarbitone).
(Largactil (R)), phenobarbitone (Gardenal (R)) and chlorpheniramine
- Do not mix phenobarbitone with other drugs in the same syringe.
- Avoid combination with erythromycin or phenobarbitone.
- Risk of increased sedation when combined with alcohol and other drugs that act on the central nervous system: diazepam (Valium (R)), phenobarbitone (Gardenal (R)) and chlorpromazine
Since the main alkaloids of the extract are hyoscyamine and hyoscine, the expected results were that, the ambulation would have been decreased significantly, compared to that of amphetamine or similar to that of phenobarbitone, due to their sedative properties.
The mice given phenobarbitone had decreased ambulation scores.
Effects of D. stramonium extract on white albino mice as compared to d-amphetamine and phenobarbitone
When an extract from the leaves was tested in laboratory mice versus phenobarbitone (a known depressant) its effect was found to be closer to that of amphetamine, i.e. behaving as a (CNS) stimulant.
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