pleiotropic

• “The findings support other studies indicating statins have pleiotropic effects or benefits beyond the reduction of cholesterol, researchers said.”

  The Wall Street Journal: Feeling Groggy? Your Brain May Be Half Asleep

• “Changes in proteins are less likely to underlie such changes because most regulatory proteins are constrained due to their pleiotropic roles in the development of different structures.”

  A Decade Spanning Single Exchange

• “This may be an important pleiotropic effect whereby rosuvastatin reduces mortality in patients with coronary artery disease.”

  The adherer effect | The Blog of Michael R. Eades, M.D.

• “Due to pleiotropic effects (stems splitting under high temperatures and water stress), GM soybeans suffer 25% higher losses than conventional soybeans (Altieri and Pengue, 2005) 5 studies between 2001 -2007 show that glyphosate applied to Roundup Ready soybeans inhibits the uptake of important nutrients essential to plant health and performance.”

  Critiquing Monsanto's Response to Vanity Fair

• “Hence, if one traits is highly adaptive but another pleiotopically linked trait is mildly deleterious, the deleterious trait can be selected for because of its pleiotropic association with the more advantageous trait.”

  Evolution

• “Due to pleiotropic effects (stems splitting under high temperatures and water stress), GM soybeans suffer 25% higher losses than conventional soybeans( Altieri and Pengue, 2005)”

  Archive 2008-04-01

• “By modularity we mean a genotype-phenotype map in which there are few pleiotropic effects among characters serving different functions, with pleiotropic effects falling mainly among characters that are part of a single functional complex.”

  Darwin and neutrality - The Panda's Thumb

• “At that time his group focused mostly on studying intracellular proteolysis, and I learnt from him that he had given up on trying to identify the mediator (s) and mechanism (s) involved in serum-induced "pleiotropic response".”

  Aaron Ciechanover - Autobiography

• “As during my studies on fatty liver I acquired experience in analyzing lipids, and since Avram felt the elucidation of the TAT proteolytic mechanism may be a too difficult undertaking for a limited-in-scope M.D. thesis, we decided to add one additional layer to the study on the "pleiotropic response" and to analyze the effect of serum on synthesis of phospholipids.”

  Aaron Ciechanover - Autobiography

• “The other possibility was to study the mechanism (s) involved in the cell's "pleiotropic response" - the immediate response of serum-starved, G0 synchronized cells to the addition of serum.”

  Aaron Ciechanover - Autobiography

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