Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. A truncated version of the protein lamin A, involved in progeria.

Etymologies

progeria +‎ -in (Wiktionary)

Examples

  • "progerin", a truncated form of the lamin A protein that causes the cell nucleus to become misshapen.

    PhysOrg.com - latest science and technology news stories

  • "progerin," a truncated form of the lamin A protein that causes the cell nucleus to become misshapen.

    New insight into 'accelerated aging' disease

  • That disease is caused by an excess of the protein progerin, a protein that we all have that in lower amounts that destroys cells to bring about the aging process.

    Nguyen Thi Phuong, Vietnamese Woman, 'Ages' 50 Years In Days

  • It found that they contained progerin and that the cells looked similar to those of children with progeria.

    New Clue in Heart Disease

  • For a long time, scientists weren't even sure whether people without progeria actually made progerin.

    New Clue in Heart Disease

  • Matt Kaeberlein, who studies the basic biology of aging at the University of Washington, said more research is needed to demonstrate that progerin levels get high enough to cause cardiovascular problems.

    New Clue in Heart Disease

  • "It is still a long ways off from saying with confidence that the accumulation of progerin during normal aging causes disease," he said.

    New Clue in Heart Disease

  • Researchers don't know a lot about progerin, a mutant form of the Lamin A protein, which is critical in organizing the genome inside the body's cells.

    New Clue in Heart Disease

  • Finding effective drugs to target progerin levels is in the early stages, he added, but the hope is to find something that "might do something for progeria as well as for normal aging."

    New Clue in Heart Disease

  • Dr. Misteli said his lab is screening large numbers of drugs to see if any of them lower progerin levels both in cells from children with progeria and cells from normally aging individuals.

    New Clue in Heart Disease

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