proteoglycans

Bioactive polysaccharides, also called proteoglycans, are a family of complex carbohydrates that are bound to proteins.

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As luck would have it, the reactions that produce glutathione also yield molecules called sulfate groups, which help generate those joint-sparing proteoglycans.

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Even when NSAIDs don't destroy the digestive tract, they may ultimately worsen people's joint problems, for they slow the production of collagen and proteoglycans, the tissues that make cartilage an effective shock absorber.

What Is Same 2008

GPC3 is a member of the glypican family of glycosylphosphatidylinositol-anchored cell-surface heparan sulfate proteoglycans.

PhysOrg.com - latest science and technology news stories 2010

GPC3 is a member of the glypican family of glycosylphosphatidylinositol-anchored cell-surface heparan sulfate proteoglycans.

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It is believed that proteoglycans such as perlecan, which are rich in the sulphated glycosaminoglycan heparan sulphate, play an important role in the retention of lipoproteins to endothelial extracellular matrix.

PLoS ONE Alerts: New Articles Alan D. Pemberton et al. 2010

Such proteoglycans are central to the "response to retention hypothesis" of atherosclerosis, proposed by Williams and Tabas

PLoS ONE Alerts: New Articles Alan D. Pemberton et al. 2010

GPC3 is a member of the glypican family of glycosylphosphatidylinositol-anchored cell-surface heparan sulfate proteoglycans.

PhysOrg.com - latest science and technology news stories 2010

Firstly, lipoproteins such as LDL to which histones have become attached may have a higher affinity for binding to endothelial proteoglycans, and may thereby lead to enhanced lipoprotein retention.

PLoS ONE Alerts: New Articles Alan D. Pemberton et al. 2010

Gooderham NJ, Davies DS, Edwards RJ (1999) Nucleosomes bind to cell surface proteoglycans.

PLoS ONE Alerts: New Articles Alan D. Pemberton et al. 2010