“The second is by a mechanism called retrotransposition - in short, the messenger RNA of a gene, instead of being used for protein synthesis, is transcribed back into a DNA sequence and inserted into the genome, forming so-called “retrogenes”.”
“They are duplicates formed through retrotransposition, and are "dead on arrival" because they are non-functional as soon as they "arrive".”
“I don't have a problem with subjecting neutral mutations and retrotransposition to further inquiry, but I sincerely doubt their validity will take any kind of hit.”
“Random genetic drift, relaxed selective pressures, retrotransposition etc. aren't going anywhere.”
“And if (as appears to be the case) retroelements (such as retrotransposons) are generally the relics of past retroviral infections, then it would appear that endosymbiosis plays an important direct role in evolution, its plays an equally important albeit indirect role through retrotransposition.”
“It is true that a retrotransposition has to occur in the germ line, just as with any mutation that gets passed on.”
“Occasional retrotransposition of autonomous elements, frequent retrotransposition of 3 'partial elements, and DNA replication slippage during retrotransposition offers a mechanistic explanation for the association of SSRs with RTE elements in lepidopteran genomes.”
“Mosaic recombination and hitchhiking on retrotransposition events to different loci were more prevalent in germ line as compared to somatic cells.”
“Januszyk K, Li PW, Villareal V, Branciforte D, Wu H, et al. (2007) Identification and solution structure of a highly conserved C-terminal domain within ORF1p required for retrotransposition of long interspersed nuclear element-1.”
“The epidemiological history of our five families shows that minicircle sequences are not only inherited, but continue to spread through the progeny genomes by hitchhiking along with retrotransposition events mediated by LINE-1.”
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