Century Dictionary and Cyclopedia
- n. The uncus.
- n. In botany, the modified tissue of the host penetrated by the mycelium of a parasite.
“The vertical axis is the estimated volume (combined over both hemispheres) of the retrohippocampal cortex, which we define as the subiculum, presubiculum, parasubiculum, and entorhinal cortex.”
“They also had size reductions in a related brain area called the subiculum, which relays the signals from the hippocampus to other areas of the brain, including the dopamine system, also known as the brain's "reward center.”
“Volume reduction in the subiculum has been associated with drug abuse and schizophrenia, as well.”
“Normal ageing is associated with reduced metabolic activity in the subiculum and the dentate gyrus, whereas reduced activity in the entorhinal cortex may be an early indicator of Alzheimer's disease”
“In looking at the longitudinal changes, we could see there was definitive evidence of a progression from the CA1 to the subiculum region, and on to the other regions of the hippocampus," Apostolova said.”
“In this study, they tracked atrophy from the CA1 as it spread to the subiculum, which matched disease progression from the MCI state to a diagnosis of Alzheimer's.”
“Again, excessive atrophy in the CA1 and subicular regions was present in cognitively normal individuals who went on to be diagnosed with MCI, and a slow progression of atrophy beyond the CA1 and subiculum to other regions was evident in those ultimately diagnosed with Alzheimer's.”
“The researchers looked at two areas within the hippocampus: the CA1 (cornu ammonis) and the subiculum.”
“They found 10 to 30 percent greater atrophy in the CA1 and subiculum of those MCI patients with premature atrophy who were later diagnosed with Alzheimer's.”
“Hippocampally-lesioned rats also had variable damage to the subiculum, postsubiculum, presubiculum, parasubiculum and entorhinal cortex.”
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