from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. Plural form of topoisomerase.
Sorry, no etymologies found.
The goal is to develop novel inhibitors of certain proteins (called topoisomerases) in order to severely restrict the ability of the bacteria to mutate and become resistant.
Why would single-stranded binding proteins and DNA topoisomerases evolve prior to DNA helicases?
T. cruzi intracellular forms leave the parasitophorous vacuole of the host cell and remain free to divide in the cytoplasm during cell division minicircles are cleaved by topoisomerases and, T. cruzi minicircles, with four adenine - and cytosine-rich (AC-rich) CSBs
Most DNA has slight negative supercoiling that is introduced by topoisomerases.
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