Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- verb Simple past tense and past participle of
PEGylate .
Etymologies
Sorry, no etymologies found.
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Examples
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In mid-May 2011, Enzon announced plans to halt the development of PEG-SN38 (EZN-2208), a PEGylated version of the active metabolite of the cancer drug, irinotecan, for the treatment of metastatic colorectal cancer (mCRC).
unknown title 2011
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PRS-050 is an anti-VEGF Vascular Endothelial Growth Factor 40 kD PEGylated Anticalin discovered and developed internally at the company.
unknown title 2011
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Peginesatide is a synthetic, PEGylated peptidic compound that binds to and activates the erythropoietin receptor and thus acts as an ESA.
unknown title 2011
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Other product candidates include PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase), which is currently in Phase II clinical development for the treatment of PKU; GALNS
Medindia Health News 2010
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Other product candidates include PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase), which is currently in Phase II clinical development for the treatment of PKU; GALNS
Medindia Health News 2010
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GALNS (N-acetylgalactosamine 6-sulfatase), which is currently in clinical development for the treatment of MPS IVA; PEG-PAL (PEGylated recombinant phenylalanine ammonia lyase), which is currently in Phase II clinical development for the treatment of PKU and BMN 195, which is currently in Phase I clinical development for the treatment of Duchenne Muscular Dystrophy.
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A new follow-up of patients from the RAPID-1 study of UCB's Cimzia (certolizumab pegol), a novel PEGylated anti-TNF, presented at EULAR showed that the patients treated with Cimzia and methotrexate who achieved a rapid and greater response to treatment by week 12 were more likely to have low disease activity two years later than patients who achieved a slower or lower response to treatment.
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PEG-SN38 or EZN-2208 is Enzon's PEGylated form of SN38, the active metabolite of the cancer drug Camptosar® (irinotecan HCl injection).
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Hematide is a novel investigational synthetic, PEGylated peptidic compound that binds to and activates the erythropoietin receptor and thus acts as an ESA.
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ALLOZYNE's lead program, AZ01, is a PEGylated interferon β for the treatment of multiple sclerosis (MS).
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