Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun Plural form of
aggresome .
Etymologies
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Examples
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Increased activity of the myostatin growth factor following MstnPP upregulation may contribute to atrophy in sIBM, however another study showed MstnPP accumulated with Aβ/AβPP within aggresomes following ER stress by proteasome inhibition in CHMFs
PLoS ONE Alerts: New Articles Carlene S. Starck et al. 2010
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Johnston JA, Illing ME, Kopito RR (2002) Cytoplasmic dynein/dynactin mediates the assembly of aggresomes.
PLoS ONE Alerts: New Articles Hongyu Ying et al. 2010
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Increased activity of the myostatin growth factor following MstnPP upregulation may contribute to atrophy in sIBM, however another study showed MstnPP accumulated with Aβ/AβPP within aggresomes following ER stress by proteasome inhibition in CHMFs
PLoS ONE Alerts: New Articles Carlene S. Starck et al. 2010
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Cultured human muscle fibers (CHMFs) overexpressing Aβ precursor protein showed an increase in MstnPP protein levels and subsequent experimental inhibition of the proteasome caused co-accumulation of MstnPP and AβPP/Aβ within aggresomes
PLoS ONE Alerts: New Articles Carlene S. Starck et al. 2010
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Cultured human muscle fibers (CHMFs) overexpressing Aβ precursor protein showed an increase in MstnPP protein levels and subsequent experimental inhibition of the proteasome caused co-accumulation of MstnPP and AβPP/Aβ within aggresomes
PLoS ONE Alerts: New Articles Carlene S. Starck et al. 2010
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Johnston JA, Illing ME, Kopito RR (2002) Cytoplasmic dynein/dynactin mediates the assembly of aggresomes.
PLoS ONE Alerts: New Articles Hongyu Ying et al. 2010
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This accumulation in aggresomes may prevent processing of MstnPP and decrease levels of circulating growth factor, as mature myostatin growth factor is absent in immunoblots of CHMFs transiently expressing AβPP
PLoS ONE Alerts: New Articles Carlene S. Starck et al. 2010
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In neurodegenerative disorders such as Alzheimer's, Huntington's and Parkinson's, intracellular deposition of aggregated proteins into inclusion bodies, Lewy bodies, or aggresomes is a prominent cytopathological feature
PLoS ONE Alerts: New Articles Hongyu Ying et al. 2010
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Even though MstnPP aggregates were localised to the cytoplasm, aggresomes and nuclear regions of sIBM tissue in previous studies
PLoS ONE Alerts: New Articles Carlene S. Starck et al. 2010
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This accumulation in aggresomes may prevent processing of MstnPP and decrease levels of circulating growth factor, as mature myostatin growth factor is absent in immunoblots of CHMFs transiently expressing AβPP
PLoS ONE Alerts: New Articles Carlene S. Starck et al. 2010
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