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- verb Present participle of
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The process of synthesizing Chitosan involves taking the shells of shrimp or crabs, grinding them to a fine powder and then deacetylating this powder.
As FE65 can simultaneously bind SET and, through Teashirt3, HDACs, this would establish a strongly transcriptionally repressed state of nucleosomes by deacetylating histone amino-terminal tails (through HDAC) and preventing them from being reacetylated (through SET inhibition of histone acetyltransferase).
Transcriptional repression can be initiated near the promoter by deacetylating specific lysine residues of nearby histone proteins.