Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Plural form of hamartoma.

Etymologies

Sorry, no etymologies found.

Examples

  • Cowden syndrome is an inherited disorder characterized by multiple tumor-like growths called hamartomas, and an increased risk of certain cancers.

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  • Patients with PHTS disorders usually develop multiple benign (noncancerous) growths known as hamartomas in different areas of the body.

    PTEN Hamartoma Tumor syndrome

  • In addition to hamartomas, patients can have other clinical features, including:

    PTEN Hamartoma Tumor syndrome

  • Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by the development of hamartomas, which are unusual tumor-like growths found in a variety of tissues

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  • TSC1 or TSC2 genes, is characterized by the development of hamartomas.

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  • MAPK-dependent phosphorylation of tuberin may lead to somatic inactivation of the hamartin / tuberin complex in tuberous sclerosis complex-associated brain hamartomas that have activated MEK1 and ERK1

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  • Usually skin hamartomas exist, and commonly (about 66\% of cases) hamartoma of the thyroid gland exists.

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  • Some lung hamartomas can compress surrounding lung tissue to a degree, but this is generally not debilitative or even noticed by the patient, especially for the more common peripheral growths.

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  • Cowden Syndrome or Cowden Disease is a serious genetic disorder characterized by multiple hamartomas.

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  • The hamartomas themselves may cause symptoms or even death, but morbidity is more often associated with increased occurrence of malignancies, usually in the breast or thyroid.

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