Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun immunology An enhancement to
electrophoresis in which the separated materials are identified byimmunoprecipitation
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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Protein electrophoresis immunofixation electrophoresis.
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Protein electrophoresis immunofixation electrophoresis.
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In addition, serum protein electrophoresis, immunofixation, nephelometric quantitation of immunoglobulins and measurement of free light chains (FLCs) are needed.
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The immunofixation results used to define CR can vary significantly due to laboratory variation.
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However, if a plasma cell proliferative disorder is diagnosed, then a 24-h urine protein electrophoresis and immunofixation are needed, and the serum FLC assay cannot be used in place of urine studies.
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It distinguishes patients who have had near disappearance in their M-spike but are still immunofixation positive from those patients who merely have a 50\% reduction in their serum M-spike.
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* nCR = Near Complete Response is defined as meeting the criteria for CR (non-detectable monoclonal protein by serum and urine), except with detectable monoclonal protein by immunofixation.
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* nCR = Near Complete Response is defined as meeting the criteria for CR (non-detectable monoclonal protein by serum and urine), except with detectable monoclonal protein by immunofixation.
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5 Second, it can be used in conjunction with serum protein electrophoresis and immunofixation when screening for the presence or absence of a monoclonal plasma cell disorder such as myeloma in place of a 24-h urine protein study.
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