Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun That which intercalates
  • noun biochemistry Any of several classes of small molecule that insert themselves into the structure of DNA

Etymologies

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Examples

  • The problem is known as strand cyclization, but Hud and his team discovered that using a molecule that binds between neighboring base pairs of DNA, known as an intercalator, can bring short pieces of DNA and RNA together in a manner that helps them create much longer molecules.

    Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7 Ani 2010

  • The problem is known as strand cyclisation, but Hud and his team discovered that using a molecule that binds between neighboring base pairs of DNA, known as an intercalator, can bring short pieces of DNA and RNA together in a manner that helps them create much longer molecules.

    Analysis 2010

  • * #3665 The novel DNA intercalator amonafide (AS1413) disrupts the cell cycle by mechanisms distinct from topo II inhibitors daunorubicin and etoposide (Senderovich et al.)

    Marketwire - Breaking News Releases 2010

  • AS1413 is a novel DNA intercalator that induces apoptotic signalling by blocking topoisomerase II binding to DNA.

    StreetInsider.com News Articles 2010

  • AS1413 (amonafide L-malate) is a DNA intercalator that induces apoptotic signalling by blocking Topoisomerase II binding to DNA.

    Marketwire - Breaking News Releases 2010

  • AS1413 (amonafide L-malate) is a DNA intercalator that induces apoptotic signalling by blocking Topoisomerase II binding to DNA.

    Marketwire - Breaking News Releases 2010

  • Hud and his research team discovered that by using a molecule that can bind in between two neighboring base pairs of DNA, known as an intercalator, they can bring short pieces of DNA and RNA together in a manner that helps them create much longer molecules.

    Livescience.com 2010

  • * #3665 The novel DNA intercalator amonafide (AS1413) disrupts the cell cycle by mechanisms distinct from topo II inhibitors daunorubicin and etoposide (Senderovich et al.)

    Marketwire - Breaking News Releases 2010

  • For an intercalator to fit between base pairs, the bases must separate, distorting the DNA strand by unwinding of the double helix.

    Citizendium, the Citizens' Compendium - Recent changes [en] 2009

  • For an intercalator to fit between base pairs, the bases must separate, distorting the DNA strand by unwinding of the double helix.

    Citizendium, the Citizens' Compendium - Recent changes [en] 2009

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