Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Any of several small regions of a cell membrane that has a distinct structure and a distinct function

Etymologies

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Examples

  • In addition, the EcR-B1 isoform of holometabolous insects had a novel microdomain at the N-terminal end.

    BioMed Central - Latest articles

  • Moreover, the novel microdomain in the isoform-specific region of the holometabolous insect EcR-B1 isoform suggests that the holometabolous insect EcR-B1 acquired additional transcriptional regulation mechanisms.

    BioMed Central - Latest articles

  • Given that the nuclear receptor AF-1 is involved in cofactor recruitment and transcriptional regulation, the microdomain structures identified in the isoform-specific A/B domains might function as signature motifs and/or as targets for cofactor proteins that play essential roles in the EcR isoform-specific AF-1 regions.

    BioMed Central - Latest articles

  • The comprehensive structural comparison revealed that the isoform-specific region of each EcR isoform contained evolutionally conserved microdomain structures and insect subgroup-specific structural modifications.

    BioMed Central - Latest articles

  • Both mitochondria depolarization and cytochrome c release are dependent on raft-like microdomain integrity, since the disruption of raft-like microdomains by methyl-β-cyclodextrin prevented mitochondria depolarization or cytochrome c release induced by GD3 or by the active form of Bid (t-Bid) [13].

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  • Nusrat A, von Eichel-Streiber C, Turner JR, Verkade P, Madara JL, et al. (2001) Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins.

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  • Hemler ME (2003) Tetraspanin proteins mediate cellular penetration, invasion, and fusion events and define a novel type of membrane microdomain.

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  • In addition, they revealed the existence of a distinct peripheral microdomain in the host cell with limited access to hemoglobin molecules indicating the concentration of substantial amounts of parasite-exported material.

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