Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective Pertaining to a
neural connection between thesubstantia nigra and thestriatum .
Etymologies
Sorry, no etymologies found.
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Examples
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When GDNF flooded a bundle of nerves known as the nigrostriatal tract, a potential target for Parkinson therapy, the obese rats lost a great deal of weight - about 80 grams.
unknown title 2009
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When GDNF flooded the nerve bundle known as the nigrostriatal tract, a potential target for Parkinson therapy, the obese rats lost a great deal of weight.
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"The results show for the first time that GDNF overexpression in an anatomical area in the brain known as the nigrostriatal tract is involved in metabolism," Mandel said.
unknown title 2009
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Once within brain, neurons producing certain neurotransmitters, such as dopaminergic nigrostriatal cells, the excess phenylalanine can inhibit enzymes (like tyrosine hydroxylase) needed to synthesize the neurotransmitters.
Santa Fe Pediatrician Regales Hawaii Legislative Committee with Dangers of Aspartame 2008
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Parkinson's disease is known to occur when dopamine neurons die in the brain's nigrostriatal pathway.
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Parkinson's disease is known to occur when dopamine neurons die in the brain's nigrostriatal pathway.
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Nrf2-knockout mice showed exacerbated gliosis and dopaminergic nigrostriatal degeneration, as determined by immunohistochemical staining of tyrosine hydroxylase in striatum (STR) and substantia nigra (SN) and by HPLC determination of striatal dopamine and 3,4 - dihydroxyphenylacetic acid (DOPAC).
PLoS ONE Alerts: New Articles Nadia G. Innamorato et al. 2010
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Nrf2-knockout mice showed exacerbated gliosis and dopaminergic nigrostriatal degeneration, as determined by immunohistochemical staining of tyrosine hydroxylase in striatum (STR) and substantia nigra
PLoS ONE Alerts: New Articles Nadia G. Innamorato et al. 2010
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Perez FA, Scouras AD, Stoll EA, Gale SD, et al. (2006) Cre recombinase-mediated restoration of nigrostriatal dopamine in dopamine-deficient mice reverses hypophagia and bradykinesia.
PLoS ONE Alerts: New Articles Michael Weisenhaus et al. 2010
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These evidences have led to the speculation that increased HO-1 levels might be the main responsible for the accumulation of free iron and subsequent damage to the nigrostriatal system
PLoS ONE Alerts: New Articles Nadia G. Innamorato et al. 2010
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