from Wiktionary, Creative Commons Attribution/Share-Alike License
- adj. Not ribosomal
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The UC San Diego web-based tools for sequencing nonribosomal peptides (at not cost to researchers) are available at: bix. ucsd.edu/nrp
This University of California, San Diego advance will finally enable scientists to rapidly characterize ring-shaped nonribosomal peptides (NRPs) - a class of natural compounds of intense interest due to their potential to yield or inspire new pharmaceuticals.
These algorithms make sense of the flood of tiny peptide fragments that are generated by machines called mass spectrometers that blast nonribosomal peptides apart and determine their sizes.
A number of different tailoring enzymes catalyze a variety of chemical modifications to the polyketide or nonribosomal peptide backbone of these secondary metabolites to enhance their structural diversity.