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permeabilisation

Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun Alternative spelling of permeabilization.

Etymologies

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Examples

  • Mitochondrial outer membrane permeabilisation (MOMP) and activation of effector caspases are key processes during apoptosis signalling.

    BioMed Central - Latest articles Heinrich Huber 2010

  • Experimentally, rapid sampling of mitochondrial permeabilisation and effector caspase activity in individual HeLa cervical cancer cells confirmed predictions of the reaction-diffusion model and demonstrated that the signalling network of apoptosis execution could efficiently translate spatial anisotropies in mitochondrial permeabilisation into a homogeneous effector caspase response throughout the cytosol.

    BioMed Central - Latest articles Heinrich Huber 2010

  • To investigate the consequences of these spatial anisotropies in mitochondrial permeabilisation on subsequent effector caspase activation, we devised a mathematical reaction-diffusion model building on a set of partial differential equations.

    BioMed Central - Latest articles Heinrich Huber 2010

  • Further systems modelling suggested that a more than 10,000-fold impaired diffusivity would be required to maintain spatial anisotropies as observed during mitochondrial permeabilisation until the time effector caspases become activated.

    BioMed Central - Latest articles Heinrich Huber 2010

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