Axin

Wnt signalling is also controlled by intracellular antagonists such as Axin, APC and Groucho which regulate β-catenin stability and activity

PLoS ONE Alerts: New Articles Eric Haÿ et al. 2009

"Axin 'yo' pardon, Mrs. Bottom, we didn't know a lady was in hearin 'or we'd never have made so bold," said old Adam.

The Miller of Old Church 1911

"Axin 'yo' pardon, Mrs. Bottom, we didn't know a lady was in hearin 'or we'd never have made so bold," said old Adam.

The Miller Of Old Church Ellen Anderson Gholson Glasgow 1909

"Axin yer pardon m'am, it may be rude, but hit ain't writ in our book of etiquette ter knock at the front door when we're huntin 'fer a man charged with murder."

The Traitor: A Story of the Fall of the Invisible Empire 1907

"Axin 'yer pardon, sir, but hev you got a pair of eyes in your head which can make out anything unusual aboard there?"

The Iron Pirate A Plain Tale of Strange Happenings on the Sea Max Pemberton 1906

Axin 'your pardon, miss, but ye looked a bit furrin and I----

The Melting-Pot Israel Zangwill 1895

Axin 'yo' pawdon, lil 'missy, fo' mentionin 'de subjeck, but our

Dorothy's Triumph Evelyn Raymond 1876

Binding of Wnt to its receptor Fz and co-receptor, low-density lipoprotein receptor related protein (LRP), releases Axin from the destruction complex, allowing amino-terminally dephosphorylated β-catenin to accumulate in the cytoplasm.

PLoS ONE Alerts: New Articles Masako Osada et al. 2010

The most studied canonical Wnt pathway leads to stabilization of β-catenin by inactivating the "destruction complex" consisting of adenomatous polyposis coli (APC), Axin and glycogen synthase kinase 3β (GSK3β).

PLoS ONE Alerts: New Articles Masako Osada et al. 2010

Axin 2 and c-Myc, although a decline in Wnt target genes could also be explained by a loss of specific TEC subsets that differentially express these genes.

PLoS ONE Alerts: New Articles Masako Osada et al. 2010