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Examples
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Aztreonam formulated with arginine has previously been approved by the FDA for intravenous administration.
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Aztreonam exhibited the highest in vitro activity against the P. aeruginosa isolates studied (64.4% susceptibility), whereas susceptibility rates of imipenem and meropenem were both 47.5 %.
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Aztreonam has potent in vitro activity against gram-negative aerobic pathogens including
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Aztreonam lysine was previously reviewed by the CHMP in March and received a negative opinion, which Gilead appealed.
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Aztreonam formulated with arginine is an FDA-approved agent for intravenous administration for treating various infections.
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Aztreonam lysine is a proprietary formulation of aztreonam developed specifically for inhalation.
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Aztreonam has potent in vitro activity against Gram-negative bacteria such as P. aeruginosa.
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Aztreonam formulated with arginine (Azactam®) is an approved agent for intravenous administration for treating various infections.
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Aztreonam lysine 75 mg powder and solvent for nebuliser solution is an inhaled antibiotic candidate for people with cystic fibrosis who have P. aeruginosa.
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Aztreonam lysine is an investigational therapy in development for people with cystic fibrosis who have pulmonary Pseudomonas aeruginosa (P. aeruginosa) infection.
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