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Examples
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Chromosomes, Boveri concluded, must carry information vital for the proper development and growth of cells.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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Cancer was not “an unnatural group of different maladies,” Boveri wrote.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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Like Flemming, who worked with salamander cells, Boveri chose to study simple cells in simple organisms, eggs from sea urchins, which he collected on the windswept beaches near Naples.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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The multiple fertilization, Boveri found, precipitated chromosomal chaos.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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To understand this natural chromosomal separation, Boveri devised a highly unnatural experiment.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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Boveri published his chromosomal theory of cancer in an elegant scientific pamphlet entitled “Concerning the Origin of Malignant Tumors” in 1914.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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Chromosomal abnormalities in cancer cells had been known since the days of von Hansemann and Boveri.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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In 1910, four years before Boveri had published his theory, Peyton Rous, working at the Rockefeller Institute, had demonstrated that cancer in chickens could be caused by a virus, soon to be named the Rous sarcoma virus, or RSV.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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The hunt for an internal, genetic cause of cancer had stalled since Boveri.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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Boveri could not put his finger on the nature of this deeper internal abnormality.
The Emperor of All Maladies Siddhartha Mukherjee 2010
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