from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A glycoprotein on the surface of killer cells that enhances binding with MHC molecules.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. a membrane glycoprotein that is found primarily on the surface of cytotoxic T cells


from The American Heritage® Dictionary of the English Language, 4th Edition

c(luster of) d(ifferentiation antigen) 8.


  • Heath WR, Shortman K (2001) Cutting edge: intravenous soluble antigen is presented to CD4 T cells by CD8 - dendritic cells, but cross-presented to CD8 T cells by CD8+ dendritic cells.

    PLoS ONE Alerts: New Articles

  • More specifically, researchers observed rapid and sustained immunological reconstitution in terms of CD4 and CD8 lymphocyte counts and high frequencies of specific CD4+ and CD8+ cells against microbial agents together with a significant reduction in post-transplant cytomegalovirus reactivation.


  • Indeed, as compared with untreated melanoma cells, pretreatment with hIFN-γ and GGTI-298 together rendered the melanoma cells more efficient at inducing the: i) activation of CD8 T lymphocytes (CD8+/CD69+); ii) proliferation of tumor-specific CD8 T cells (MelanA-MART1/TCR+); iii) secretion of hIFN-γ; and iv) anti-melanoma specific cytotoxic cells.

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  • Researchers have long suspected that immune cells known as CD8 lymphocytes secrete something that can immobilize HIV.

    The Body's Own Aids Rx?

  • This vaccine was designed to create an immune response that would produce high levels of a cell called CD8, or "the killer T cell."

    Anatomy of a Failure

  • In theory, disease-fighting blood cells called CD8 T-cells might be stimulated this way to actually control HIV without the need for further drugs.

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  • When they looked at a specific subgroup of T cells, known as CD8+ T cells, they found that the patients could be separated into two distinct groups based on their long term prognosis, with one group having more disease relapses or 'flares' than the other. - latest science and technology news stories

  • The fluorescently stained image shows a type of killer white blood cell, called CD8+ T cells (colored green), invading the brain and - Articles related to Healthy Diet Could Slow Or Reverse Early Effects Of Alzheimer's Disease

  • By studying monkeys at the Oregon National Primate Research Center naturally infected with CMV, researchers demonstrated that CMV re-infection can only take place when the virus is able to evade a key portion of the immune system called CD8+ T cells. - latest science and technology news stories

  • Initially, the researchers identified another group of blood cells called CD8 which are involved in the autoimmune process and are supposedly responsible for destroying CD4 cells in the immune system.



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