Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun A glycoprotein on the surface of killer cells that enhances binding with MHC molecules.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun a membrane glycoprotein that is found primarily on the surface of cytotoxic T cells
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
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Examples
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More specifically, researchers observed rapid and sustained immunological reconstitution in terms of CD4 and CD8 lymphocyte counts and high frequencies of specific CD4+ and CD8+ cells against microbial agents together with a significant reduction in post-transplant cytomegalovirus reactivation.
unknown title 2009
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More specifically, researchers observed rapid and sustained immunological reconstitution in terms of CD4 and CD8 lymphocyte counts and high frequencies of specific CD4+ and CD8+ cells against microbial agents together with a significant reduction in post-transplant cytomegalovirus reactivation.
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More specifically, researchers observed rapid and sustained immunological reconstitution in terms of CD4 and CD8 lymphocyte counts and high frequencies of specific CD4+ and CD8+ cells against microbial agents together with a significant reduction in post-transplant cytomegalovirus reactivation.
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Heath WR, Shortman K (2001) Cutting edge: intravenous soluble antigen is presented to CD4 T cells by CD8 - dendritic cells, but cross-presented to CD8 T cells by CD8+ dendritic cells.
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Indeed, as compared with untreated melanoma cells, pretreatment with hIFN-γ and GGTI-298 together rendered the melanoma cells more efficient at inducing the: i) activation of CD8 T lymphocytes (CD8+/CD69+); ii) proliferation of tumor-specific CD8 T cells (MelanA-MART1/TCR+); iii) secretion of hIFN-γ; and iv) anti-melanoma specific cytotoxic cells.
PLoS ONE Alerts: New Articles Guillaume Sarrabayrouse et al. 2010
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Indeed, as compared with untreated melanoma cells, pretreatment with hIFN-γ and GGTI-298 together rendered the melanoma cells more efficient at inducing the: i) activation of CD8 T lymphocytes (CD8+/CD69+); ii) proliferation of tumor-specific CD8 T cells (MelanA-MART1/TCR+); iii) secretion of hIFN-γ; and iv) anti-melanoma specific cytotoxic cells.
PLoS ONE Alerts: New Articles Guillaume Sarrabayrouse et al. 2010
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Researchers have long suspected that immune cells known as CD8 lymphocytes secrete something that can immobilize HIV.
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This vaccine was designed to create an immune response that would produce high levels of a cell called CD8, or "the killer T cell."
Anatomy of a Failure 2007
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In theory, disease-fighting blood cells called CD8 T-cells might be stimulated this way to actually control HIV without the need for further drugs.
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When they looked at a specific subgroup of T cells, known as CD8+ T cells, they found that the patients could be separated into two distinct groups based on their long term prognosis, with one group having more disease relapses or 'flares' than the other.
PhysOrg.com - latest science and technology news stories 2010
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