Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A glycoprotein on the surface of killer cells that enhances binding with MHC molecules.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. a membrane glycoprotein that is found primarily on the surface of cytotoxic T cells

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

c(luster of) d(ifferentiation antigen) 8.

Examples

  • Heath WR, Shortman K (2001) Cutting edge: intravenous soluble antigen is presented to CD4 T cells by CD8 - dendritic cells, but cross-presented to CD8 T cells by CD8+ dendritic cells.

    PLoS ONE Alerts: New Articles

  • More specifically, researchers observed rapid and sustained immunological reconstitution in terms of CD4 and CD8 lymphocyte counts and high frequencies of specific CD4+ and CD8+ cells against microbial agents together with a significant reduction in post-transplant cytomegalovirus reactivation.

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  • Indeed, as compared with untreated melanoma cells, pretreatment with hIFN-γ and GGTI-298 together rendered the melanoma cells more efficient at inducing the: i) activation of CD8 T lymphocytes (CD8+/CD69+); ii) proliferation of tumor-specific CD8 T cells (MelanA-MART1/TCR+); iii) secretion of hIFN-γ; and iv) anti-melanoma specific cytotoxic cells.

    PLoS ONE Alerts: New Articles

  • Researchers have long suspected that immune cells known as CD8 lymphocytes secrete something that can immobilize HIV.

    The Body's Own Aids Rx?

  • This vaccine was designed to create an immune response that would produce high levels of a cell called CD8, or "the killer T cell."

    Anatomy of a Failure

  • In theory, disease-fighting blood cells called CD8 T-cells might be stimulated this way to actually control HIV without the need for further drugs.

    ANC Daily News Briefing

  • When they looked at a specific subgroup of T cells, known as CD8+ T cells, they found that the patients could be separated into two distinct groups based on their long term prognosis, with one group having more disease relapses or 'flares' than the other.

    PhysOrg.com - latest science and technology news stories

  • The fluorescently stained image shows a type of killer white blood cell, called CD8+ T cells (colored green), invading the brain and

    WN.com - Articles related to Healthy Diet Could Slow Or Reverse Early Effects Of Alzheimer's Disease

  • By studying monkeys at the Oregon National Primate Research Center naturally infected with CMV, researchers demonstrated that CMV re-infection can only take place when the virus is able to evade a key portion of the immune system called CD8+ T cells.

    PhysOrg.com - latest science and technology news stories

  • Initially, the researchers identified another group of blood cells called CD8 which are involved in the autoimmune process and are supposedly responsible for destroying CD4 cells in the immune system.

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