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Examples
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The researchers, led by Lu, reasoned that if Cdk oscillation was the only cycle-setting pacemaker in the cell, blocking it would cause the cell cycle to stall.
PhysOrg.com - latest science and technology news stories PhysOrg Team 2010
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In experiments published Thursday in Cell, they tested the hypothesis by watching what happens to another important protein in the cell cycle known as Cdc14, which normally moves away from the nucleolus, activates and begins antagonizing Cdk as the cell exits mitosis.
PhysOrg.com - latest science and technology news stories PhysOrg Team 2010
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In experiments published Thursday in Cell, they tested the hypothesis by watching what happens to another important protein in the cell cycle known as Cdc14, which normally moves away from the nucleolus, activates and begins antagonizing Cdk as the cell exits mitosis.
PhysOrg.com - latest science and technology news stories PhysOrg Team 2010
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They then blocked Cdk oscillation and overt cell-cycle progression, and surprisingly found that the periodic Cdc14 activation/inactivation continued just as it would in a normally dividing cell.
PhysOrg.com - latest science and technology news stories PhysOrg Team 2010
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The experiments suggest that, although Cdc14 activity oscillated at constant Cdk levels, its frequency was controlled by several different Cdk activities, which indicates that autonomous cell-cycle oscillators may coordinate each other through a phenomena called phase-locking.
PhysOrg.com - latest science and technology news stories PhysOrg Team 2010
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The researchers, led by Lu, reasoned that if Cdk oscillation was the only cycle-setting pacemaker in the cell, blocking it would cause the cell cycle to stall.
PhysOrg.com - latest science and technology news stories PhysOrg Team 2010
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(Cdk); Cdk's independent oscillating activity can establish the pace and order of cell cycle events.
PhysOrg.com - latest science and technology news stories PhysOrg Team 2010
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The experiments suggest that, although Cdc14 activity oscillated at constant Cdk levels, its frequency was controlled by several different Cdk activities, which indicates that autonomous cell-cycle oscillators may coordinate each other through a phenomena called phase-locking.
PhysOrg.com - latest science and technology news stories PhysOrg Team 2010
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They then blocked Cdk oscillation and overt cell-cycle progression, and surprisingly found that the periodic Cdc14 activation/inactivation continued just as it would in a normally dividing cell.
PhysOrg.com - latest science and technology news stories PhysOrg Team 2010
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(Cdk); Cdk's independent oscillating activity can establish the pace and order of cell cycle events.
PhysOrg.com - latest science and technology news stories PhysOrg Team 2010
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