Charcot-Marie-Tooth love



from Wiktionary, Creative Commons Attribution/Share-Alike License

  • adj. Describes any of various genetic disorders whose primary symptom is peripheral neuropathy.
  • n. Any of the Charcot-Marie-Tooth disorders.


from Wiktionary, Creative Commons Attribution/Share-Alike License

Named for Jean-Martin Charcot, Pierre Marie, and Howard Henry Tooth.


  • For instance, he said, a well-known neurological disorder, Charcot-Marie-Tooth disease, is caused by structural changes of DNA at sites of recombination.

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  • The paper was finally published as James R. Lupski et al., “Whole-genome sequencing in a patient with Charcot-Marie-Tooth neuropathy,” New England Journal of Medicine, March 10, 2010.

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  • James R. Lupski et al., “DNA duplication associated with Charcot-Marie-Tooth disease type 1A,” Cell 66 1991, 219–232.

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  • There are roughly 6,000 such diseases, including Charcot-Marie-Tooth, a neurological disorder, and Miller Syndrome, characterized by severe facial and limb deformities.

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  • A more severe meuropathy in a single extremity, and certainly in multiple extremities, does justify screening for the varied hereditary pressure palsy syndromes and variants of Charcot-Marie-Tooth syndrome.

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  • Having barely recovered from a spinal fusion, I heard my doctor say, Glenda, you have Charcot-Marie-Tooth Disease, an incurable neuromuscular disease that affects your peripheral nerves.

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  • The status of MacCulloch remains in question as battles Charcot-Marie-Tooth syndrome, a neurological disorder that slowly eats away at the nerves in the body's extremities.

  • * Smith has submitted two other disease-specific stem cell lines for possible inclusion on the registry, including one that carries Charcot-Marie-Tooth disease.

    Yahoo! News: Business - Opinion

  • Charcot-Marie-Tooth Association says the disease is a nonfatal, noncontagious genetic condition in the Muscular Dystrophy family.

    Yahoo! News: Business - Opinion

  • -- Dr. James Lupski of the Baylor College of Medicine in Houston studied his own entire DNA map and sequenced the genomes of family members -- including his deceased grandfather -- to diagnose the mutation causing his rare genetic nerve disease, called Charcot-Marie-Tooth syndrome.

    Reuters: Top News


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