Cravatt

Having identified a key player responsible for the aggressive behavior of cancer cells, Cravatt and Nomura wanted to better understand MAGL's role.

THE MEDICAL NEWS 2010

Cravatt, who is also a member of the Skaggs Institute for Chemical Biology at Scripps Research, added: "It is not only necessary but sufficient for the aggressive phenotype."

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"We have shown that cancer cells have their own pathways to produce free fatty acids, which will enable them to become more aggressive," says Cravatt.

THE MEDICAL NEWS 2010

Cravatt, who is also a member of the Skaggs Institute for Chemical Biology at Scripps Research, added: "It is not only necessary but sufficient for the aggressive phenotype."

Medindia Health News 2010

"It is not only necessary but sufficient for the aggressive phenotype," says Cravatt, who is also a member of the Skaggs Institute for Chemical Biology at Scripps Research.

THE MEDICAL NEWS 2010

"It is not only necessary but sufficient for the aggressive phenotype," says Cravatt, who is also a member of the Skaggs Institute for Chemical Biology at Scripps Research.

THE MEDICAL NEWS 2010

"It might have a better safety profile because it does not target a general survival mechanism common to all cells," explains Cravatt.

THE MEDICAL NEWS 2010

"We have shown that cancer cells have their own pathways to produce free fatty acids, which will enable them to become more aggressive," says Cravatt.

THE MEDICAL NEWS 2010

Adam GC, Cravatt BF (2003) Activity-based protein profiling in vivo using a copper (i) - catalyzed azide-alkyne [3+2] cycloaddition.

PLoS ONE Alerts: New Articles Sandeep Ravindran et al. 2009

In addition to Cravatt and Nomura, co-authors of the study also include Jonathan Long, Sherry Niessen, and Heather Hoover from Scripps Research and Shu-Wing Ng from Harvard Medical School.

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