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Examples
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Tombal B, Miller K, Boccon-Gibod L, et al. Degarelix vs. leuprolide treatment in patients with advanced prostate cancer: PSA failures during a randomised, phase III trial (CS21) [abstract].
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Degarelix achieved fast testosterone suppression; by day 3, testosterone levels were ≤ 0.5 ng/mL in ~96% of degarelix-treated patients in contrast to none of those receiving leuprolide (Figure 1).
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Degarelix: a novel gonadotropin-releasing hormone (GnRH) receptor blocker -- results from a
unknown title 2009
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Degarelix is a new synthetic GnRH blocker modeled on natural GnRH.
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Degarelix: a novel gonadotropin-releasing hormone (GnRH) receptor blocker -- results from a
unknown title 2009
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Degarelix was as effective as leuprolide in suppressing testosterone levels from Day 28 to the end of the study (Day 364), with 97. 2% of the degarelix patients maintaining medical castrate levels compared with 96. 4% for leuprolide.
unknown title 2009
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Degarelix is awaiting approval in other key global markets.
The Medical Quack 2009
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"Degarelix was at least as effective as leuprolide in achieving and maintaining castrate levels of testosterone."
The Medical Quack 2009
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Degarelix was as effective as leuprolide in suppressing testosterone levels from Day 28 to the end of the study (Day 364), with 97. 2% of the degarelix patients maintaining medical castrate levels compared with 96. 4% for leuprolide.
unknown title 2009
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Degarelix has a direct and logical mechanism of action with strong GnRH receptor binding.
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