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Examples
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In mammals, a heteromeric dimer of the transcriptional activators, CLOCK and BMAL1, induces the expression of several genes by interacting with the enhancer elements of their promoters known as the E-box.
Why should medical students study evolution? Here's an example. - The Panda's Thumb 2007
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Our recent studies of P1. 1 in vitro and in a human trophoblast cell line (Jeg3) revealed that interactions of placental nuclear protein (s) with the E-box element at position -340 are required for full promoter activity.
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Our recent studies of P1. 1 in vitro and in a human trophoblast cell line (Jeg3) revealed that interactions of placental nuclear protein (s) with the E-box element at position -340 are required for full promoter activity.
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The aim of this work was to identify and characterise the placental E-box (-340) - binding protein (s) (E-BP) as a step towards understanding how the expression of Cyp19 is regulated in the bovine placenta.
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The aim of this work was to identify and characterise the placental E-box (-340) - binding protein (s) (E-BP) as a step towards understanding how the expression of Cyp19 is regulated in the bovine placenta.
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Furthermore, scatter plot analysis of P1. 1 activity vs. USF binding to the E-box revealed a strong positive correlation between the two parameters.
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The significance of the E-box was confirmed in cultured primary bovine trophoblasts.
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The aim of this work was to identify and characterise the placental E-box (-340) - binding protein (s) (E-BP) as a step towards understanding how the expression of Cyp19 is regulated in the bovine placenta.
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The significance of the E-box was confirmed in cultured primary bovine trophoblasts.
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Furthermore, scatter plot analysis of P1. 1 activity vs. USF binding to the E-box revealed a strong positive correlation between the two parameters.
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