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The second drug is Erlotinib, which is distributed under the brand name Tarceva.
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The second drug is Erlotinib, which is distributed under the brand name Tarceva.
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Erlotinib is one of a class of drugs that specifically inhibits an important cell-surface molecule known as the epidermal growth factor receptor (EGFR), which is highly expressed in some forms of cancer, including lung cancer.
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Erlotinib (Tarceva®) is marketed by Genentech and OSI Pharmaceuticals.
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Erlotinib did best against EGFR mutations, vandetanib for high VEGFR-2 expression and the erlotinib-bexarotene fared best with Cyclin D1 defects or amplified numbers of the EGFR gene.
PhysOrg.com - latest science and technology news stories PhysOrg Team 2010
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Erlotinib and gefitinib are tyrosine kinase inhibitors that block ErbB1 receptor activation, whereas trastuzumab is a monoclonal antibody that has been designed to specifically inhibit ErbB2 receptor activation.
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Erlotinib (Tarceva®) is marketed by Genentech and OSI Pharmaceuticals.
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Erlotinib, marketed as Tarceva (TM), is an inhibitor of the EGFR tyrosine kinase.
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Erlotinib (Tarceva®) is marketed by Genentech and OSI Pharmaceuticals.
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Erlotinib, marketed as Tarceva ™, is an inhibitor of the EGFR tyrosine kinase.
THE MEDICAL NEWS Editors 2010
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