Galectin-3

BGMD - News, a life sciences company focused on the development and commercialization of novel, biomarker-based diagnostics, announced today that it will host an interactive webcast, "Role of Galectin-3 in Therapeutic and Cardiovascular Outcomes -- Results from Leading Studies Presented at the European Society of Cardiology Congress 2011."

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"Galectin-3, cardiovascular risk factors, and outcome in the general population"

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Galectin-3 is known to be increased in patients with heart failure and is believed to be a critical mediator in the development of cardiac fibrosis.

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Galectin-3 is a unique carbohydrate-binding lectin, or protein, that binds to carbohydrates called beta-galactosides.

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Pharmacological Inhibition of Galectin-3 Attenuates Adverse Cardiac Remodeling and Heart Failure , researched whether a special natural carbohydrate molecule that binds to a specific site on the galectin-3 protein can inhibit fibrosis, reduce heart failure development and reduce mortality.

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Galectin-3 is known to be increased in patients with heart failure and is believed to be a critical mediator in the development of cardiac fibrosis.

unknown title 2011

Galectin-3 is a unique carbohydrate-binding lectin, or protein, that binds to carbohydrates called beta-galactosides.

unknown title 2011

In addition, the Company will also discuss its launch progress, label extension plans and distribution partner updates for its marketed BGM Galectin-3 www.bg-medicine.com .

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Galectin-3 has been implicated in a variety of biological processes important in the development and progression of heart failure, and is believed to be a primary mediator of progressive cardiac fibrosis (abnormal thickening and stiffening of the heart muscle) and adverse remodeling (changes in the structure of the heart).

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Genetic Disruption of Galectin-3 Prevents Adverse Cardiac Remodeling , investigated whether disruption of the galectin-3 pathway blocks heart failure development by means that normally induce heart failure.

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