Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun genetics regulatory gene and RNA gene responsible for brain development; and of the
neocortex in humans.
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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In a computer-based search for pieces of DNA that have undergone the most change since the ancestors of humans and chimps diverged, "Human Accelerated Region 1" or HAR1, was a clear standout.
And now the news 2006
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There is more to learn about HAR1 RNA, but already a Belgian colleague of Pollard's has shown that it is made in specific nerve cells within the brain's developing cerebral cortex.
PhysOrg.com - latest science and technology news stories 2010
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Pollard and colleagues named the DNA segment HAR1, for "human accelerated region."
PhysOrg.com - latest science and technology news stories 2010
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Pollard's colleagues subsequently showed that HAR1 encodes RNA.
PhysOrg.com - latest science and technology news stories 2010
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HAR1 proves to mark a genetic region that is expressed early in the development of the neocortex; HAR152 is near the gene encoding a protein called neurogenin-2 that is expressed in a region of the hippocampus with a central role in learning and memory; and HAR2 is near a gene with strong expression in the hand, perhaps playing some role in human-specific hand coordination.
NPR Topics: News 2010
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HAR1, HAR1F, is expressed in human Cajal-Retzius cells that are thought to play a crucial role in redirecting migrating neurons during development.
BRAINETHICS Nowitall 2009
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HAR1 is not a protein-coding sequence but belongs to a non-coding RNA sequence.
BRAINETHICS Nowitall 2009
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what happens when we activate HAR1 in other animals.
Newsvine - Get Smarter Here JoulesBeef 2009
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