HER-2

The formal name is “human epidermal growth factor receptor,” and it is also known as HER-2, c-erbB-2, ErbB-2, and ERBB2.

The 10 Best Questions Dede Bonner 2008

The formal name is “human epidermal growth factor receptor,” and it is also known as HER-2, c-erbB-2, ErbB-2, and ERBB2.

The 10 Best Questions Dede Bonner 2008

The Personalized Medicine Coalition, a nonprofit advocacy group including industry, academia and government organizations, estimated the cost of Herceptin therapy per patient at about $79,000 for those who weren't tested for HER-2 and were more likely to have a poorer response to the treatment.

Companies Aim to Personalize Therapy Goran Mijuk 2010

Targeted therapy with trastuzumab (Herceptin) can help the 20 percent of breast-cancer patients who have a protein called human epidermal growth factor receptor 2 (HER-2).

Breast cancer treatments: Know your options 2010

The HER-2 gene helps to control how cells grow, divide and repair themselves.

Companies Aim to Personalize Therapy Goran Mijuk 2010

Since it was established through the PathVysion test that her breast cancer was due to too much of the HER-2 gene, she was told to take Roche's Herceptin.

Companies Aim to Personalize Therapy Goran Mijuk 2010

If a tumor is present, the antibodies, with the nanoparticles in tow, naturally recognize and bind to the HER-2 receptor of breast-cancer cells.

Researchers Create Better Ways to Spot Cancer Cells Shirley S. Wang 2011

A key product, he says, is Abbott's PathVysion test, which measures the HER-2 gene, a primary target for the breast cancer drug Herceptin, made by Roche.

Companies Aim to Personalize Therapy Goran Mijuk 2010

Only 30% to 40% of breast cancers contain the HER-2 receptor, the target in the current experiment.

Researchers Create Better Ways to Spot Cancer Cells Shirley S. Wang 2011

But since it was clear that her cancer was due to the HER-2 gene, doctors kept treating her with Herceptin.

Companies Aim to Personalize Therapy Goran Mijuk 2010