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Examples
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There are a few districts where a good populist Dem could probably give a DINO incumbent a good run -- IL-3 comes to mind.
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IL-3 withdrawal causes receptor-interacting protein (RIP) 1 cleavage into C-terminal fragments of 30 and 25 kDa, and only cleavage leading to the former was prevented by zVAD-fmk. siRNA experiments demonstrated that generation of the 25-kDa fragment was due to a Bcl-2-modulated release of the mitochondrial serine protease high temperature requirement protein A2 (HtrA2)/Omi.
Naturejobs - All Jobs Lieselotte Vande Walle 2010
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January 22, 2009 -- Today, Congressman Dan Lipinski (IL-3) released the following statement:
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January 22, 2009 -- Today, Congressman Dan Lipinski (IL-3) released the following statement:
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IL-3 withdrawal causes receptor-interacting protein (RIP) 1 cleavage into C-terminal fragments of 30 and 25 kDa, and only cleavage leading to the former was prevented by zVAD-fmk. siRNA experiments demonstrated that generation of the 25-kDa fragment was due to a Bcl-2-modulated release of the mitochondrial serine protease high temperature requirement protein A2 (HtrA2)/Omi.
Naturejobs - All Jobs Lieselotte Vande Walle 2010
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Interestingly, knockdown of HtrA2/Omi afforded protection against IL-3 withdrawal-induced death in the presence of zVAD-fmk, demonstrating a role for HtrA2/Omi in caspase-independent cell death during growth factor withdrawal by cleaving RIP1.
Naturejobs - All Jobs Lieselotte Vande Walle 2010
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We therefore adapted the standard protocol for generation of bone marrow-derived macrophages by inducing expansion of progenitor cells with the cytokines IL-3, IL-6 and SCF in the presence of macrophage colony stimulating factor (M-CSF).
Naturejobs - All Jobs Gabriele Weintz 2010
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IL-3 withdrawal causes receptor-interacting protein (RIP) 1 cleavage into C-terminal fragments of 30 and 25 kDa, and only cleavage leading to the former was prevented by zVAD-fmk. siRNA experiments demonstrated that generation of the 25-kDa fragment was due to a Bcl-2-modulated release of the mitochondrial serine protease high temperature requirement protein A2 (HtrA2)/Omi.
Naturejobs - All Jobs Lieselotte Vande Walle 2010
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Interestingly, knockdown of HtrA2/Omi afforded protection against IL-3 withdrawal-induced death in the presence of zVAD-fmk, demonstrating a role for HtrA2/Omi in caspase-independent cell death during growth factor withdrawal by cleaving RIP1.
Naturejobs - All Jobs Lieselotte Vande Walle 2010
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Interestingly, knockdown of HtrA2/Omi afforded protection against IL-3 withdrawal-induced death in the presence of zVAD-fmk, demonstrating a role for HtrA2/Omi in caspase-independent cell death during growth factor withdrawal by cleaving RIP1.
Naturejobs - All Jobs Lieselotte Vande Walle 2010
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