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Examples
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One drug, Lapatinib, can halve the speed of growth of breast cancer in one in five women with an aggressive form of the disease.
Never Yet Melted 2009
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Dr Gillian Leng, Nice deputy chief executive, said 'The committee concluded that Lapatinib is not a cost-effective use of
Never Yet Melted 2009
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In March, NICE ruled against the use of two drugs, Lapatinib and Sutent, that prolong the life of those with certain forms of breast and stomach cancer.
Of NICE and Men 2009
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"Lapatinib was approved for advanced breast cancer in 2007," Baselga said.
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Lapatinib, in combination with capecitabine, is authorised in more than 90 countries worldwide for the treatment of patients with advanced or metastatic breast cancer, whose tumours over-express ErbB2.
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Lapatinib inhibits the tyrosine kinase enzyme activities of ErbB1 and ErbB2, which blocks a series of biochemical signals associated with tumour growth.
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Lapatinib is the first oral, small-molecule, dual-targeted therapy for metastatic breast cancer that over-express ErbB2.
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Lapatinib is the first oral, small-molecule, dual-targeted therapy for metastatic breast cancer that over-express ErbB2.
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Lapatinib, in combination with an aromatase inhibitor (AI), is indicated for the treatment of post-menopausal women with hormone receptor (HR) - positive, HER2 (ErbB2) over-expressing metastatic breast cancer and for whom chemotherapy is currently not intended.
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Pivot X, et al. Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer.
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