Ligand

The drugs target a protein called RANK Ligand, which helps regulate cells called osteoclasts that break down bone.

FDA Panel Votes Against Expanding Use of Amgen Drug Xgeva Jennifer Corbett Dooren 2012

Pfizer, via Wyeth, licensed bazedoxifene from Ligand Pharmaceuticals Inc.

Pfizer Set to Seek Aprela Nod Peter Loftus 2012

Skeleton Crew osteoclast The drugs target a protein called RANK Ligand, which helps regulate cells called osteoclasts that break down bone.

Week in Words Erin McKean 2012

Prolia targets a protein called RANK Ligand, which helps regulate cells called osteoclasts that break down bone.

Amgen Drug Shown to Delay Fractures in Cancer Patients 2010

To treat or prevent osteoporosis, denosumab is designed to inhibit a protein known as RANK Ligand that is involved with bone destruction.

FDA Panel Suggests Limits for Amgen's Bone Drug 2009

Ligand Pharmaceuticals disclosed plans to buy cash-strapped drug developer Neurogen for $11 million in stock plus the potential for millions more in cash, giving Ligand access to a partnership with large-cap Merck.

Fannie and Freddie Surge, Continuing Their Rally 2009

Drug maker Ligand fell 22 cents, or 8%, at 2.54, while Neurogen ended flat at 20 cents.

Fannie and Freddie Surge, Continuing Their Rally 2009

In order to treat or prevent osteoporosis, denosumab is designed to inhibit a protein known as RANK Ligand that's involved with bone destruction.

Risks Seen on Bone Drug 2009

Ligand Pharmaceuticals fell 1.29, or 36%, to 2.30.

Matrix Service and New Market Climb; 2008

The U.S. Food and Drug Administration said Promacta, a treatment Ligand is developing for patients affected by chronic thrombocytopenic purpura, or ITP, in partnership with GlaxoS.ithKline, was unable to significantly reduce bleeding when compared with a placebo.

Matrix Service and New Market Climb; 2008