Meredith's

Grey's Anatomy's season finale: Meredith's misdeed tears Seattle Grace apart

Grey's Anatomy Postmortem: What's Next for the Seattle Grace Docs? 2011

In the season finale of Grey's Anatomy, Meredith's (Ellen Pompeo) decision to tamper with the Alzheimer's clinical trial was put front and center, as her actions fractured her marriage with Derek (Patrick Dempsey).

Grey's Anatomy Postmortem: What's Next for the Seattle Grace Docs? 2011

The episode will imagine all the ways Meredith's life would be different if her mother, who suffered from Alzheimer's before she died in Season 3, was alive and well.

Kate Burton Checks Back Into Grey's for Alternate Universe Episode 2011

Grey's Anatomy's season finale: Meredith's misdeed tears Seattle Grace apart

Grey's Anatomy Postmortem: What's Next for the Seattle Grace Docs? 2011

There hasn't even been the usual brilliant, subtle expressions that Sandra Oh is so good at to indicate that Cristina is at least thinking about the impact on her marriage, such as during the scene in episode 5 where she is fawning over Zola, Derek and Meredith's baby, and Owen leaves the room.

Ask Matt: Globes Weirdness, Dexter, Person of Interest, Charlie Sheen, and More! 2011

In order to save Meredith's career, Webber takes one for the team and steps down as The Chief.

Grey's Anatomy: Where Were We and What's Next? 2011

I also love, story-wise and character-wise, the evolution of Meredith's character, this woman who, I remember saying in a bunch of interviews, she will never have kids.

Grey's Anatomy Scoop: MerDer Happiness, a Cristina-Owen Explosion and the Alt-Reality 2012

With emergency amputation as a Grey's Anatomy metaphor, Dr. Hunt has an epiphany about his wife's struggle with her unwanted pregnancy, bolstered by Meredith's speech about having been "raised by a Cristina."

As Seen and Heard on TV: Matt's Week in Review 2011

Really, the premise is what would have happened if Meredith's mother had never had Alzheimer's, if Meredith had been raised as a bright and shiny person.

Grey's Anatomy Scoop: MerDer Happiness, a Cristina-Owen Explosion and the Alt-Reality 2012

It brings people together (Dwight and Kelly), it causes fires (to Meredith's hair), and, one year, it even prompted a surprise visit to rehab (seriously, Meredith, it's time to just accept that you have a drinking problem).

Exclusive Office Video: Can the Christmas Party Cure Robert California's Heartache? 2011