Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • An ancient region of southwest Asia between the Tigris and Euphrates rivers in modern-day Iraq. Probably settled before 5000 B.C., the area was the home of numerous early civilizations, including Sumer, Akkad, Babylonia, and Assyria. It declined in importance after Mongol invaders destroyed its extensive irrigation system in A.D. 1258.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • proper n. A region in Southwest Asia spanning from the rivers Euphrates and Tigris that is the site of one of the most ancient civilizations in the history of man.
  • proper n. The British Mandate of Mesopotamia, a League of Nations mandate from 1920 to 1932 that was the precursor to the independent state of Iraq.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. the land between the Tigris and Euphrates; site of several ancient civilizations; part of what is now known as Iraq

Etymologies

From Ancient Greek Μεσοποταμία (Mesopotamía), from μέσος (mésos, "between") + ποταμός (potamós, "river"), because Mesopotamia is located between rivers Euphrates and Tigris. (Wiktionary)

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