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Examples
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Mipomersen cuts production of a protein critical to the production and transport of low-density lipoproteins, often called bad cholesterol.
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As part of the deal -- under which Genzyme said it would spend $325 million up front in a licensing and investment pact -- Genzyme will get partial rights to Mipomersen, a potential blockbuster in a large market.
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Genzyme has said Mipomersen could initially launch in 2009 and get a first-label expansion in 2010.
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"Mipomersen has the potential to set a new standard of care for this difficult-to-treat disease."
THE MEDICAL NEWS Editors 2010
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"Mipomersen has the potential to set a new standard of care for this difficult-to-treat disease."
THE MEDICAL NEWS Editors 2010
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Mipomersen was discovered by Isis, of Carlsbad, Calif., and licensed to Genzyme, which is based in Cambridge, Mass.
The Seattle Times 2010
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Mipomersen was discovered by Isis, of Carlsbad, Calif., and licensed to Genzyme, which is based in Cambridge, Mass.
Fore, right! The Associated Press 2010
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Mipomersen is designed to decrease the formation of apolipoprotein B (the main structural protein in LDL cholesterol) and its release from the liver or intestine.
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Mipomersen is an apo-B synthesis inhibitor designed to reduce LDL cholesterol levels by preventing the formation of atherogenic lipids.
GEN News Highlights 2010
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"Mipomersen could make a major difference for these patients."
THE MEDICAL NEWS Editors 2010
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