Myb

Finally, there is a large number of oncogene products which are located in the nucleus of the cell, i.e. Myc, Myb, Fos,

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This virus was created based on the G207 backbone, where the viral gene ICP34. 5 was not deleted but rather expressed under the control of a cancer specific promoter Myb.

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Figure 4: Defect in the survival of c-Myb-deficient DP thymocytes.

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Figure 8: DP thymocytes that lack c-Myb are unable to support the development of CD1d deficient

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Right, GFP expression in transduced c-Myb-deficient thymocytes.

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This virus was created based on the G207 backbone, where the viral gene ICP34. 5 was not deleted but rather expressed under the control of a cancer specific promoter Myb.

Scientific Blogging jenwong 2010

This virus was created based on the G207 backbone, where the viral gene ICP34. 5 was not deleted but rather expressed under the control of a cancer specific promoter Myb.

Scientific Blogging jenwong 2010

Myb-related HTH motif; coil, predicted coil domain; RCT, homology to the RAP1 C terminus; NLS, nuclear localization signal.

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This virus was created based on the G207 backbone, where the viral gene ICP34. 5 was not deleted but rather expressed under the control of a cancer specific promoter Myb.

Scientific Blogging jenwong 2010

Figure 7: Lower expression of SLAMF1 and SLAMF6 in c-Myb-deficient mice.

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